Sodium Cyclamate Effect on Nondisjunction Frequency of Drosophila melanogaster Meigen
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Nov 1, 2017
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Abstract
Sodium cyclamate is one of the artificial sweeteners that have potential health concerns. In this research, a study was conducted to examine the effects of sodium cyclamate administration on nondisjunction frequency of Drosophila melanogaster. ♂ the homozygous ebony body was crossbred with ♀ homozygous wild-type fly and was fed with food containing 0% (control group), 5%, 10%, and 15% sodium cyclamate. Based on ANOVA result, F count was 29.578 with the p-value 0.000 < 0.05. Thus, the null hypothesis was rejected and research hypothesis states there were significant differences of nondisjunction frequency was accepted. Flies treated with sodium cyclamate had significantly higher nondisjunction than the control flies. Administration of 15% sodium cyclamate caused nondisjunction with the greatest frequency.
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PUTRI, Eka Pratama; FAUZI, Ahmad.
Sodium Cyclamate Effect on Nondisjunction Frequency of Drosophila melanogaster Meigen.
Proceedings of the International Conference on Green Technology, [S.l.], v. 8, n. 1, p. 154-158, nov. 2017.
ISSN 2580-7099.
Available at: <http://conferences.uin-malang.ac.id/index.php/ICGT/article/view/530>. Date accessed: 08 may 2024.
doi: https://doi.org/10.18860/icgt.v8i1.530.
Section
Biology
References
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[3] Caballero B, Allen L, Prentice A, editors. Encyclopedia of Human Nutrition, Second Edition. Oxford: Elsevier Ltd; 2005. 212 p.
[4] Oddy DJ. From Plain Fare to Fusion Food: British Diet from the 1890s to the 1990s. Suffolk: Boydell Press; 2003. 201 p.
[5] Brillas E, Huitle CAM, editors. Synthetic Diamond Films: Preparation, Electrochemistry, Characterization and Applications. Wiley; 2011. 46 p.
[6] International Food Information Service, editor. IFIS Dictionary of Food Science and Technology, Second Edition. West Sussex: John Wiley & Sons Ltd, 2009, 392 p.
[7] Pavia DL, Lampman GM, Kriz GS, Engel RG. A Small Scale Approach to Organic Laboratory Techniques. Boston: Cengage Learning; 2015, 443 p.
[8] Pena CT. Empty Pleasures: The Story of Artificial Sweeteners from Saccharin to Splenda. Greensboro: The University of North Carolina Press. 2010. 55p.
[9] Whitney E, DeBruyne LK, Pinna K, Rolfes SR. Nutrition for Health and Health Care. Wadsworth: Wadsworth Cengage Learning; 2007. 272 p.
[10] Hens K, Cutas D, Horstkotter D, editors. Parental Responsibility in the Context of Neuroscience and Genetics. Dordrecht: Springer; 2017.
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[14] Jones RE, Lopez KH. Human Reproductive Biology. London: Academic Press; 2014. 100 p.
[15] Jennings BH. Drosophila – a versatile model in biology & medicine. Materialstoday [Internet]. 2011 May [cited 2017 June 21]; 14(5): 190-195. Available from: http://www.sciencedirect.com/science/article/pii/S1369702111701134 DOI: 10.1016/S1369-7021(11)70113-4.
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[17] Koehler KE, Hawley RS, Sherman S, Hassold T. Recombination and nondisjunction in humans and flies. Hum Mol Genet [Internet]. 1996 September. [cited 2017 June 2017]; 5 (Supplement_1): 1495-1504. Available from: https://academic.oup.com/hmg/article/5/Supplement_1/1495/663563/Recombination-and-nondisjunction-in-humans-and DOI: 10.1093/hmg/5.Supplement_1.1495.
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[19] Christiansen FB. Theories of Population Variation in Genes and Genomes. Princeton: Princeton University Press; 2008. 297 p.
[20] Khanna P. Essentials of Genetics. New Delhi: I. K. International Publishing House Pvt. Ltd; 2009. 236 p.
[21] Appels R, Morris R, Gill BS, May CE. Chromosome Biology. New York: Springer Science+Business Media, LLC; 2003. 63 p.
[22] Scandalios JG. Advances in Genetics, Volume 26. San Diego: Academic Press, Inc; 1989, 183 p.
[23] Ramel C, Magnusson J. Chemical Induction of Nondisjunction in Drosophila. Environmental Health Perspectives [Internet]. 1979 Aug [cited 2017 June 25]; 31: 59-66. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637649/ DOI: 10.2307/3429143
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[25] Committee on the Evaluation of Cyclamate for Carcinogenicity, Commission on Life Sciences National Research Council. Evaluation of Cyclamate for Carcinogenicity. Washington, D. C.: National Academy Press; 1985. 56 p.
[26] Gold LS, editor. Carcinogenic Potency Database, Endocrine Disruptors. North Carolina: NIEHS; 1999. 529 p.
[27] Nguyen T. Food and Cancer: A Guide to Understanding the Secondary Causes of Cancer. EnCognitive.com; 2015.