The Offspring Number of Drosophila melanogaster Meigen Consuming Monosodium Glutamate for Two Generations
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Nov 1, 2017
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Abstract
Monosodium Glutamate (MSG) is one of the flavor enhancers that most commonly used in various foods but its safety is still in doubt. In this research, a study was conducted to examine the effects of MSG administration on offspring number of Drosophila melanogaster for two generations. D. melanogaster ♂ wild-type strain was crossed with ♀ wild-type strain in glass bottle were fed with two different concentrations of 2.0% and 2.5% of MSG. Along with treated, the control flies were also set up without MSG. Based on ANOVA result, F count concentration variable on offspring number was 25.159 with the p-value 0.000 < 0.05 and F count generation variable on offspring number was 14.095 with the p-value 0.001 < 0.05. Administration of 2.0% MSG caused the increasing of offspring number but at 2.5% level, MSG caused the decreasing of offspring number. Furthermore, first-generation had a significantly higher offspring number than the second generation. The result indicated there was an accumulation of negative impacts of MSG consumption in the second generation.
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ATIKA, Anggun Risma; FAUZI, Ahmad.
The Offspring Number of Drosophila melanogaster Meigen Consuming Monosodium Glutamate for Two Generations.
Proceedings of the International Conference on Green Technology, [S.l.], v. 8, n. 1, p. 159-163, nov. 2017.
ISSN 2580-7099.
Available at: <http://conferences.uin-malang.ac.id/index.php/ICGT/article/view/531>. Date accessed: 24 apr. 2024.
doi: https://doi.org/10.18860/icgt.v8i1.531.
Section
Biology
References
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[23] Das RS, Ghosh SK. Long term effects of monosodium glutamate on spermatogenesis following neonatal exposure in albino mice – a histological study. Nepal Med Coll J [Internet]. 2010 [cited 2017 June 26]; 12(3): 149-153. Available from: nmcth.edu/images/gallery/Editorial/I3kxErs_das.pdf
[24] Oladipo IC, Adebayo EA, Kuye OM. Effects of Monosodium Glutamate in Ovaries of Female Sprague-Dawley Rats. Int.J.Curr.Microbiol.App.Sci [Internet]. 2015 [cited 2017 June 26]; 4(5): 737-745. Available from: http://www.ijcmas.com
[25] Eweka AO, Om'Iniabohs FAE. Histological Studies of the Effects of Monosodium Glutamate on the Ovaries of Adult Wistar Rats. Ann Med Health Sci Res [Internet]. 2011 Jan[cited 2017 June 26]; 1(1): 37-43. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507099/
[26] Sarfaraz S. Effects of Monosodium Glutamate on Drosophila melanogaster. LAP LAMBERT Academic Publishing; 2014.
[27] Ataseven N, Yuzbasnoglu D, Keskin AC, Unal F. Genotoxicity of monosodium glutamate. Food and Chemical Toxicology [Internet]. 2016 May [cited 2017 June 26]; 91: 8-18. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26929995 DOI: 10.1016/j.fct.2016.02.021
[2] Burdock GA. Fenaroli's Handbook of Flavor Ingredients, Fifth Edition. Boca Raton: CRC Press; 2005. 1339 p.
[3] Sardesai V. Introduction to Clinical Nutrition, Third Edition. Boca Raton: CRC Press; 2012. 529 p.
[4] Ziegler E, Ziegler H, editors. Flavourings: Production, Composition, Applications, Regulations. Weinheim: Wiley-VCH; 1998. 317 p.
[5] Centamore A. Tasting Wine and Cheese: An Insider's Guide to Mastering the Principles of Pairing. Beverly: Quarry Books, 2015. 14 p.
[6] Deshpande SS. Handbook of Food Toxicology. New York: Marcel Dekker, Inc; 2002. 269 p.
[7] Watson DH, editor. Food Chemical Safety: Additives. Cambridge: Woodhead Publishing Limited; 2003. 156 p.
[8] Myers RL. The 100 Most Important Chemical Compounds: A Reference Guide: A Reference Guide. Westport: Greenwood Press; 2007. 183 p.
[9] Sharma A. Monosodium glutamate-induced oxidative kidney damage and possible mechanisms: a mini-review. Journal of Biomedical Science [Internet]. 2015 Oct [cited 2017 June 23];22(93):1-6. Available from: https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-015-0192-5 DOI: 10.1186/s12929-015-0192-5
[10] Eweka AO, Om'Iniabohs FAE. Histological studies of the effecst of monosodium glutamate on the kidney of adult Wistar rats. Electron J Biomed [Internet]. 2008 May [cited 2017 June 23]. Available from: http://biomed.uninet.edu/2008/n2/eweka.html.
[11] Husarova V, Ostatnikova D. Monosodium Glutamate Toxic Effects and Their Implications for Human Intake: A Review. JMED Research [Internet]. 2013 Dec [cited 2017 June 23];2013(2013):1-12. Available from: www.talkingaboutthescience.com/studies/Husarova2013.pdf DOI: 10.5171/2013.608765
[12] DEvere R, Calvert M. Navigating Smell and Taste Disorders. New York: Demos Medical Publishing; 2011. 63 p.
[13] Darombi EO, Onyema OO, Farombi EO. Monosodium glutamate-induced oxidative damage and genotoxicity in the rat: modulatory role of vitamin C, vitamin E and quercetin. Human & Ekperimental Toxicology [Internet]. 2006 May [cited 2017 June 23];25(2006): 251-259. Available from: http://journals.sagepub.com/doi/pdf/10.1191/0960327106ht621oa DOI: 10.1191/0960327106ht621oa
[14] Rezael R, Knabe DA, Tekwe CD, Dahanayaka S, Ficken MD, Dielder E, et al. Dietary supplementation with monosodium glutamate is safe and improves growth performance in postweaning pigs. Amino acids [Internet]. 2012 Nov [cited 2017 June 23];44(3): 911-923. Available from: https://checkout.springer.com/checkout/cart?1&wt_mc=ThirdParty.SpringerLink.3.EPR653.AbstractPage_Article-new DOI: 10.1007/s00726-012-1420-x
[15] Jennings BH. Drosophila – a versatile model in biology & medicine. Materialstoday [Internet]. 2011 May [cited 2017 June 21]; 14(5): 190-195. Available from: http://www.sciencedirect.com/science/article/pii/S1369702111701134 DOI: 10.1016/S1369-7021(11)70113-4.
[16] Fauzi A, Corebima AD, Zubaidah S. The Utilization of Drosophila melanogaster as a Model Organism in Genetics I and Genetics II Courses in Faculty of Mathematics and Natural Science, State University of Malang. In: International Conference on Education and Training 2016 [Internet]; 2016 Nov 4-6; Malang; Faculty of Education, State University of Malang; 2016 [cited 2017 June 23]; p: 51-56. Available from: http://icet.fipum.com/wp-content/uploads/2017/03/PROCEEDINGS-2ND-ICET-BOOK-1-.pdf
[17] Fauzi A, Corebima AD, Zubaidah S. The Fluctuation of Adult Filial Number and Eclosion Time of Drosophila melanogaster that Exposed by Mobile Phone in Multiple Generations. In: the 6th Annual Basic Science International Conference [Internet]; 2016 March 2-3; Atria Hotel and Conference, Malang, Indonesia; Faculty of Mathematics & Sciences, Brawijaya University; 2016 June [cited 2017 June 23]; p: 124-128. Available from: http://basic.ub.ac.id/files/proceeding/PROCEEDINGS-BASIC-2016.pdf
[18] Simpson SJ, Casas J, editors. Advances in Insect Physiology: Locust Phase Polyphenism: An Update, volume 36. London: Academic Press; 2009. 84 p.
[19] Dempster JP, McLean IFG. Insect Populations In theory and in practice. Dordrecht: Springer Science+Business Media; 1998. 196.
[20] Neethu BK, Babu YR, Harini BP. Flavors supplemented in diet regulate the hatchability and viability in Drosophila. Dros. Inf. Serv [Internet]. 2014 [cited 2017 June 26];2013(2013):24-28. Available from: http://www.ou.edu/journals/dis/DIS97/Neethu%2024.pdf
[21] Igwebuike UM, Ochiogu IS, Ihedinihu BC, Ikokide JE, Idika IK: The effects of oral administration of monosodium glutamate (msg) on the testicular morphology and cauda epididymal sperm reserves of young and adult male rats. Veterinarski Arhiv. [Internet]. 2011 [cited 2017 June 26]; 81(4): 523-534. Available from: http://www-staro.vef.unizg.hr/vetarhiv/papers/2011-81-4-9.pdf
[22] Kadir RE, Omotoso GO, Balogun T, Oyewopo AO. Effects of Monosodium Glutamate on Semen Quality and the Cytoarchitecture of the Testis of Adult Wistar Rats. International Journal of Biomedical and Health Sciences [Internet]. 2011 March [cited 2017 June 26]; 7(1): 39-46. Available from: https://www.researchgate.net/profile/Olaiya_Omotoso/publication/256437842_Effects_of_Monosodium_Glutamate_on_Semen_Quality_and_the_Cytoarchitecture_of_the_Testis_of_Adult_Wistar_Rats/links/00b495228cef218970000000/Effects-of-Monosodium-Glutamate-on-Semen-Quality-and-the-Cytoarchitecture-of-the-Testis-of-Adult-Wistar-Rats.pdf?origin=publication_detail
[23] Das RS, Ghosh SK. Long term effects of monosodium glutamate on spermatogenesis following neonatal exposure in albino mice – a histological study. Nepal Med Coll J [Internet]. 2010 [cited 2017 June 26]; 12(3): 149-153. Available from: nmcth.edu/images/gallery/Editorial/I3kxErs_das.pdf
[24] Oladipo IC, Adebayo EA, Kuye OM. Effects of Monosodium Glutamate in Ovaries of Female Sprague-Dawley Rats. Int.J.Curr.Microbiol.App.Sci [Internet]. 2015 [cited 2017 June 26]; 4(5): 737-745. Available from: http://www.ijcmas.com
[25] Eweka AO, Om'Iniabohs FAE. Histological Studies of the Effects of Monosodium Glutamate on the Ovaries of Adult Wistar Rats. Ann Med Health Sci Res [Internet]. 2011 Jan[cited 2017 June 26]; 1(1): 37-43. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507099/
[26] Sarfaraz S. Effects of Monosodium Glutamate on Drosophila melanogaster. LAP LAMBERT Academic Publishing; 2014.
[27] Ataseven N, Yuzbasnoglu D, Keskin AC, Unal F. Genotoxicity of monosodium glutamate. Food and Chemical Toxicology [Internet]. 2016 May [cited 2017 June 26]; 91: 8-18. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26929995 DOI: 10.1016/j.fct.2016.02.021