Senna occidentalis and Cyanthillium patulum: Indonesian Herbs as Source for Antimalarial Agents
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Published
Dec 31, 2019
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Abstract
As stated in history, antimalarial agents are closely related to natural product research. Senna occidentalis and Cyanthillium patulum are among many potential medicinal plants based on ethno-traditional knowledge. This study was conducted to profile the activity for antimalarial from the crude methanol extract of the plant, which were collected from Malang,-East Java and Klaten-Central Java, Indonesia. Antimalarial assay against Plasmodium falciparum was done in vitro. Chemical identification using Dragendorff's reagent and spectral analysis from 1H-NMR spectroscopy was conducted. The results demonstrate that the extract of leaves of S. occidentalis constitutes typical phenolic backbones whereas C. patulum constitutes sugar derivatives and
terpenoids. Crude methanol extracts of the two species possessed significant antimalarial activity. The further experiment is required to define the responsible antimalarial compounds.
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How to Cite
PRATAMA, Antonius Nugraha Widhi et al.
Senna occidentalis and Cyanthillium patulum: Indonesian Herbs as Source for Antimalarial Agents.
Proceedings of the International Conference on Green Technology, [S.l.], v. 10, p. 9-12, dec. 2019.
ISSN 2580-7099.
Available at: <http://conferences.uin-malang.ac.id/index.php/ICGT/article/view/1111>. Date accessed: 27 apr. 2024.
doi: https://doi.org/10.18860/icgt.v10i0.1111.
Section
Pharmacy
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Dhankhar, “Cassia occidentalis L.: A review on its ethnobotany,
phytochemical and pharmacological profile.,” Fitoterapia, vol. 81, no. 4, pp. 223–230, 2010.
[22] K. Murugan et al., “Mosquitocidal and antiplasmodial activity of Senna occidentalis (Cassiae) and Ocimum basilicum (Lamiaceae) from Maruthamalai hills against Anopheles stephensi and Plasmodium falciparum,” Parasitol. Res., vol. 114, no. 10, pp. 3657–3664, 2015.
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